سامانه همایش‌ها TSTA | ثبت‌نام و ارسال مقاله کنفرانس‌ها و کنگره‌های ملی

صفحه اصلی / سی و دومین کنفرانس ملی و دهمین کنفرانس بین المللی مهندسی زیست پزشکی ایران

Phase-Amplitude Coupling of Event-Related Potentials during VCPT Task in Dyslexic Subjects

نویسندگان :

Mahdi Mollaei¹ Maryam Mohebbi² Reza Rostami³

1- دانشگاه صنعتی خواجه نصیرالدین طوسی 2- دانشگاه صنعتی خواجه نصیرالدین طوسی 3- دانشگاه تهران

کلمات کلیدی :

Dyslexia،ERP،Phase-Amplitude coupling،VCPT

چکیده :

Dyslexia can be categorized as a learning problem with neurodevelopmental roots. People with dyslexia usually have unexpected problems with reading and deciphering letters and symbols. Such a disorder not only profoundly impacts academic achievements but also affects social and emotional aspects of one’s life. For this reason, early detection of dyslexia seems to be necessary to provide dyslexic people with more appropriate educational curriculum and support. In this study, we provide more support for the capability of Visual Continuous Performance Task (VCPT) in the early detection of dyslexia. We used Phase-amplitude coupling (PAC) to extract biomarkers for dyslexia detection. Besides, we discuss how coupling and connectivity measures are prone to spurious connections and why surrogate corrections need to be performed. Our results revealed that while Delta-Gamma and Theta-Gamma coupling shows strong statistical significance, Alpha-Gamma PAC is more effective in distinguishing dyslexic from typically reading subjects, reflecting active top-down attentional control. Cross-frequency coupling patterns highlighted the prominence of temporal and frontal electrodes, whereas occipital electrodes contributed less than expected, suggesting that attention and cognitive control mechanisms play a major role during VCPT. Alpha-Gamma PAC acts as a dynamic gating mechanism, selectively amplifying task-relevant neural activity and suppressing irrelevant signals, thereby supporting efficient performance.