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صفحه اصلی / سی و دومین کنفرانس ملی و دهمین کنفرانس بین المللی مهندسی زیست پزشکی ایران

Plasma Electrolytic Oxidation-Derived HAp–Ta₂O₅ Coatings on Ti6Al4V for Biomedical Applications

نویسندگان :

Milad Hosseini¹ Jafar Khalil allafi² Mir saman Safavi³

1- دانشگاه صنعتی سهند تبریز 2- دانشگاه صنعتی سهند تبریز 3- دانشگاه صنعتی سهند تبریز

کلمات کلیدی :

Ti6Al4V dental implant،Plasma Electrolytic Oxidation،HAp-Ta2O5 coating،Biological characteristics

چکیده :

This study focused on enhancing hydroxyapatite (HAp) coatings by incorporating tantalum pentoxide (Ta₂O₅) nanoparticles at concentrations ranging from 0 to 1.5 g/L into the electrolyte solution. The HAp-Ta₂O₅ composite coatings were applied to Ti6Al4V implants using the plasma electrolytic oxidation (PEO) technique. While increasing Ta₂O₅ concentration did not significantly alter the phase composition, the addition of 1.5 g/L resulted in a denser and more compact coating. In vitro biocompatibility assessments using the MG-63 cell line demonstrated that Ta₂O₅ incorporation improved cell viability and proliferation. Immunofluorescence imaging confirmed more live cells and fewer dead cells on the composite coatings. These results suggest that the HAp-Ta₂O₅ coatings offer a promising approach to developing bioactive metallic implants with enhanced osteoblast compatibility.